Medical Condition

pediatric cancer

Total Trials

8

Recruiting Now

8

Trial Phases

Phase 1, Phase 2

Pediatric oncology trials address cancers that are biologically distinct from their adult counterparts — including acute lymphoblastic leukemia (the most common childhood cancer), brain tumors (glioma, medulloblastoma, DIPG), Ewing sarcoma, neuroblastoma, and Wilms tumor. The Children's Oncology Group (COG), funded by the NCI, is the world's largest cooperative pediatric cancer research organization and leads the majority of US clinical trials for patients under 18.

Current trials investigate NTRK, ALK, and ROS1 inhibitors in pediatric solid tumors harboring these fusions, immunotherapy for pediatric solid tumors (where adult response rates have not been replicated), ONC201 for DIPG and H3K27M-mutated diffuse midline gliomas, and CAR-T cell therapies in relapsed/refractory pediatric ALL. The FDA's RACE for Children Act now requires industry sponsors to study therapies in pediatric patients when pediatric relevance exists.

Pediatric cancer trials are conducted at COG-member children's hospitals. Families should contact the COG at childrensoncologygroup.org or their treating pediatric oncologist for enrollment information.

Frequently Asked Questions — pediatric cancer Clinical Trials

How many clinical trials are currently recruiting for pediatric cancer?

ClinicalMetric currently tracks 8 actively recruiting clinical trials for pediatric cancer, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 8. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for pediatric cancer?

pediatric cancer research spans Phase 1 (1 trial), Phase 2 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a pediatric cancer clinical trial?

Eligibility criteria for pediatric cancer trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 1

Phase 2

Sun Yat-sen University

View Trial →

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: April 2026 · Data Methodology