← Browse by Condition
Medical Condition

patent foramen ovale

Total Trials
4
Recruiting Now
4
Trial Phases
Various

ClinicalMetric tracks all active clinical trials for patent foramen ovale sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — patent foramen ovale Clinical Trials

How many clinical trials are currently recruiting for patent foramen ovale?
ClinicalMetric currently tracks 4 actively recruiting clinical trials for patent foramen ovale, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 4. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for patent foramen ovale?
patent foramen ovale research spans multiple clinical trial phases. Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a patent foramen ovale clinical trial?
Eligibility criteria for patent foramen ovale trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Top Sponsors
Peking University Third Hospital 1 trial
Recross Cardio, Inc. 1 trial
First Affiliated Hospital Xi'an Jiaotong University 1 trial
Encore Medical Inc. 1 trial

Recruiting Clinical Trials

NCT06953622
Recruiting
Establishment of a Clinical and Prognostic Follow-up Cohort of Migraine Patients With Patent Foramen Ovale
Enrollment
330 pts
Location
China
Sponsor
Peking University Third Hospit...
View Trial →
NCT07172464
Recruiting
Early Feasibility Study (EFS) Evaluating Percutaneous Repair of the Atrial Septum With a Novel PFO Occluder: The PROTEA-PFO Study
Enrollment
15 pts
Location
United States
Sponsor
Recross Cardio, Inc.
View Trial →
NCT07170176
Recruiting
Effects of PFO Closure on Glymphatic Function and Clinical Symptoms in Patients With Migraine
Enrollment
150 pts
Location
China
Sponsor
First Affiliated Hospital Xi'a...
View Trial →
NCT05537753
Recruiting
Encore PFO Closure Device - The PerFOrm Trial
Enrollment
500 pts
Location
United States
Sponsor
Encore Medical Inc.
View Trial →

Related Conditions

cryptogenic stroke (2) migraine (1) pfo (1) pfo patent foramen ovale (1) pfo associated stroke (1) migraine disorders (1) right to left shunt cardiac (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology