Medical Condition

parkinson disease pd

Total Trials

9

Recruiting Now

9

Trial Phases

Phase 2, Phase 1

Parkinson's disease research has expanded from symptomatic management (dopaminergic drugs, DBS) toward neuroprotective and disease-modifying strategies targeting alpha-synuclein aggregation β€” the protein implicated in Lewy body pathology. Prodromal biomarker studies now aim to identify patients years before motor symptoms appear, when intervention may be most effective.

Trials test alpha-synuclein antibodies (prasinezumab, cinpanemab), GBA1 gene therapy, adaptive deep brain stimulation (aDBS), GLP-1 agonists (liraglutide, semaglutide), and nilotinib for neuroprotection. Skin biopsy and cerebrospinal fluid alpha-synuclein assays are emerging as enrollment biomarkers.

Disease-modifying trials often restrict enrollment to early-stage patients (Hoehn & Yahr 1β€“2.5) within a few years of diagnosis to capture sufficient disease duration for benefit detection.

Frequently Asked Questions — parkinson disease pd Clinical Trials

How many clinical trials are currently recruiting for parkinson disease pd?

ClinicalMetric currently tracks 9 actively recruiting clinical trials for parkinson disease pd, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 9. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for parkinson disease pd?

parkinson disease pd research spans Phase 1 (2 trials), Phase 2 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a parkinson disease pd clinical trial?

Eligibility criteria for parkinson disease pd trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 1

Phase 2

Top Sponsors

Istanbul Physical Medicine Rehabilitation Training and Research Hospital 1 trial

Ankara University 1 trial

Ke Dong, MD 1 trial

Universidad San Jorge 1 trial

Northumbria University 1 trial

Recruiting Clinical Trials

NCT07308795

Recruiting

The Ultrasonographic Evaluation of Abdominal Accessory Respiratory Muscle Thickness in Patients With Parkinson's Disease: Correlation With Disease Severity and Expiratory Respiratory Muscle Strength

Istanbul Physical Medicine Reh...

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NCT07536542

Recruiting

Effects of Dual-Task Training on Upper Extremity Function in Parkinson's Disease

Different Frequency Temporal Interference Stimulation on Bilateral Subthalamic Nucleus for Parkinson's Disease

Acute Effects of Capacitive-Resistive Radiofrequency Therapy in People With Parkinson's Disease

Universidad San Jorge

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NCT07281794

Recruiting

Clinical Validity of the DANU Sports System for Gait and Balance Assessment in Parkinson's Disease

Northumbria University

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NCT07312110 Phase 2

Recruiting

D-SPARK: A Clinical Trial of D-Serine for Modifying Parkinson's Disease Progression

Haukeland University Hospital

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NCT07572071 Phase 1

Recruiting

Safety and Feasibility of Bilateral Striatal Transplantation of DopaCell in Parkinson's Disease

Testing if PDR-001 Can Safely and Effectively Remove Harmful Brain Protein in Parkinson's Disease

L-THEANINE AND MEDITERRANEAN DIET ON RBD, GI FUNCTION, AND INFLAMMATION IN PARKINSON'S DISEASE

Related Conditions

maximum inspiratory pressure (1) maximum expiratory pressure (1) abdominal accessory respiratory muscle thickness (1) healthy controls (1) parkinson s disease (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology