Diabetes clinical trials span both type 1 (autoimmune beta-cell destruction) and type 2 (insulin resistance) disease, with growing focus on the overlapping spectrum including latent autoimmune diabetes in adults (LADA) and monogenic forms. Research priorities include beta-cell preservation in newly diagnosed type 1 patients, weight-loss-independent glucose control, and prevention of cardiovascular and renal complications.
Current trials evaluate GLP-1/GIP dual agonists (tirzepatide analogs), oral insulin formulations, closed-loop artificial pancreas systems, immunotherapy for type 1 delay, SGLT2 inhibitors in non-diabetic heart failure, and stem-cell-derived islet transplantation. Lifestyle intervention trials also remain an active category.
Many trials separate type 1 and type 2 cohorts; baseline HbA1c, duration of disease, and eGFR are common eligibility criteria.
Frequently Asked Questions — obesity and diabetes mellitus type 2 Clinical Trials
How many clinical trials are currently recruiting for obesity and diabetes mellitus type 2?
ClinicalMetric currently tracks 1 actively recruiting clinical trials for obesity and diabetes mellitus type 2, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 1. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for obesity and diabetes mellitus type 2?
obesity and diabetes mellitus type 2 research spans multiple clinical trial phases. Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a obesity and diabetes mellitus type 2 clinical trial?
Eligibility criteria for obesity and diabetes mellitus type 2 trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Top Sponsors
Baylor College of Medicine 1 trial
Recruiting Clinical Trials
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional.
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Last Reviewed: April 2026 ·
Data Methodology