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lymphoblastic lymphoma precursor b lymphoblastic lymphoma leukaemia recurrent

Total Trials
1
Recruiting Now
1
Trial Phases
Phase 1, Phase 2

Lymphoma trials span diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, Hodgkin lymphoma, mantle cell lymphoma, and T-cell lymphomas — each with distinct biology and treatment response. CAR-T cell therapy has established a new standard in relapsed/refractory DLBCL, and trials now aim to move this approach earlier in the treatment sequence.

Active trials evaluate bispecific antibodies (mosunetuzumab, epcoritamab, glofitamab), next-generation CAR-T cell products (CD19/CD22 dual targets, BCMA-targeting), BTK inhibitors in B-cell lymphomas, and total metabolic volume on PET as a predictive biomarker for treatment adaptation.

Trial Phases
Phase 1
1
Phase 2
1
Top Sponsors
Princess Maxima Center for Pediatric Oncology 1 trial

Recruiting Clinical Trials

NCT05751044 Phase 1, Phase 2
Recruiting

HEM-iSMART-B: Dasatinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies

Enrollment
26 pts
Location
Austria, Belgium, De...
Sponsor
Princess Maxima Center for Ped...
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