HIV/AIDS clinical trials have shifted from managing a lethal disease to optimizing long-acting treatment that frees patients from daily oral pills β€” and increasingly, toward cure strategies that eliminate the viral reservoir. The approval of monthly injectable cabotegravir/rilpivirine and twice-yearly lenacapavir for prevention (PrEP) demonstrate how profoundly trial evidence has reshaped HIV management.
Current trials evaluate broadly neutralizing antibodies (bNAbs) for reservoir clearance, long-acting injectables (islatravir, lenacapavir combinations), mRNA-based therapeutic vaccines, and latency-reversing agents to expose hidden viral reservoirs for immune clearance. HIV prevention trials (PrEP) actively recruit high-risk populations including MSM, transgender women, and PWID.
Frequently Asked Questions — hiv aids and infections Clinical Trials
How many clinical trials are currently recruiting for hiv aids and infections?
ClinicalMetric currently tracks 1 actively recruiting clinical trials for hiv aids and infections, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 1. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for hiv aids and infections?
hiv aids and infections research spans Phase 2 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a hiv aids and infections clinical trial?
Eligibility criteria for hiv aids and infections trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Top Sponsors
Imperial College London 1 trial
Recruiting Clinical Trials
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional.
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Last Reviewed: April 2026 ·
Data Methodology