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her2 negative breast cancer

Total Trials
4
Recruiting Now
4
Trial Phases
Phase 1, Phase 4, Phase 2

Cancer clinical trials represent the largest single category of recruiting studies worldwide, encompassing everything from early-phase safety studies of novel oncology drugs to large Phase 3 comparisons against current standard-of-care chemotherapy regimens. The field has accelerated dramatically with the rise of immunotherapy, targeted therapies, and CAR-T cell treatments that have transformed outcomes for previously untreatable malignancies.

Trials include checkpoint inhibitors (PD-1/PD-L1 agents), KRAS inhibitors, ADC (antibody-drug conjugates), combination chemotherapy regimens, radiation protocols, and surgical technique comparisons. Many trials stratify by biomarker status (PD-L1 expression, TMB, MSI-H) to identify patients most likely to benefit.

The NCI, pharmaceutical sponsors, and academic cancer centers collectively fund thousands of oncology trials annually across every cancer type.

Frequently Asked Questions — her2 negative breast cancer Clinical Trials

How many clinical trials are currently recruiting for her2 negative breast cancer?
ClinicalMetric currently tracks 4 actively recruiting clinical trials for her2 negative breast cancer, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 4. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for her2 negative breast cancer?
her2 negative breast cancer research spans Phase 1 (1 trial), Phase 2 (1 trial), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a her2 negative breast cancer clinical trial?
Eligibility criteria for her2 negative breast cancer trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
1
Phase 2
1
Phase 4
1
Top Sponsors
Indiana University 1 trial
Regor Pharmaceuticals Inc. 1 trial
Fudan University 1 trial
SOLTI Breast Cancer Research Group 1 trial

Recruiting Clinical Trials

NCT06744465
Recruiting

NearWave Optical Molecular Monitoring

Enrollment
15 pts
Location
United States
Sponsor
Indiana University
View Trial →
NCT07524322 Phase 1
Recruiting

Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors

Enrollment
63 pts
Location
United States
Sponsor
Regor Pharmaceuticals Inc.
View Trial →
NCT06230055 Phase 4
Recruiting

Intrathecal Chemotherapy Through Ommaya Reservoir Upon Her-2 Negative Breast Cancer With Leptomeningeal Metastasis

Enrollment
37 pts
Location
China
Sponsor
Fudan University
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NCT05982093 Phase 2
Recruiting

Elacestrant With/Without Triptorelin in Premenopausal Women With Luminal Breast Cancer

Enrollment
96 pts
Location
Spain
Sponsor
SOLTI Breast Cancer Research G...
View Trial →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology