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Medical Condition
gestational hypertension
Total Trials
5
Recruiting Now
5
Trial Phases
Phase 4
Hypertension remains the most common treatable cardiovascular risk factor globally, yet blood pressure control rates remain suboptimal despite multiple effective drug classes. Clinical trials now investigate novel mechanisms including aldosterone synthase inhibitors, renal denervation devices, and RNA-based therapies targeting angiotensinogen to achieve durable pressure reduction with minimal pill burden.
Active research includes zilebesiran (RNA interference targeting angiotensinogen), baxdrostat (aldosterone synthase inhibitor), ultrasound renal denervation (Symplicity HTN-4), and resistant hypertension approaches combining SGLT2 inhibitors with MRA spironolactone. Ambulatory blood pressure monitoring is increasingly used as the primary endpoint instead of clinic readings.
Frequently Asked Questions — gestational hypertension Clinical Trials
How many clinical trials are currently recruiting for gestational hypertension?
ClinicalMetric currently tracks 5 actively recruiting clinical trials for gestational hypertension, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 5. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for gestational hypertension?
gestational hypertension research spans Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a gestational hypertension clinical trial?
Eligibility criteria for gestational hypertension trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 4 1
Top Sponsors
1 trial
1 trial
1 trial
1 trial
1 trial
Recruiting Clinical Trials
NCT06953115
Recruiting
Enrollment
210 pts
Location
Mexico
Sponsor
Fundación Internacional René M...
NCT05676476
Recruiting
Enrollment
132 pts
Location
United States
Sponsor
University of Alabama at Birmi...
NCT06632379 Phase 4
Recruiting
Enrollment
76 pts
Location
United States
Sponsor
Ohio State University
NCT06234332
Recruiting
Enrollment
2,800 pts
Location
China
Sponsor
Peking University
NCT06920563
Recruiting
Enrollment
296 pts
Location
United States
Sponsor
Ochsner Health System
Related Conditions
preeclampsia (3) hypertensive disorder of pregnancy (1) hypertensive disorders of pregnancy (1) health problems in pregnancy (1) pregnancy outcomes (1) gestational diabetes (1) preterm birth (1) obesity (1) mother infant interaction (1) child development (1) anemia (1) pre eclampsia complicating pregnancy (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology