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dlbcl diffuse large b cell lymphoma

Total Trials
8
Recruiting Now
8
Trial Phases
Phase 3, Phase 2

Lymphoma trials span diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, Hodgkin lymphoma, mantle cell lymphoma, and T-cell lymphomas β€” each with distinct biology and treatment response. CAR-T cell therapy has established a new standard in relapsed/refractory DLBCL, and trials now aim to move this approach earlier in the treatment sequence.

Active trials evaluate bispecific antibodies (mosunetuzumab, epcoritamab, glofitamab), next-generation CAR-T cell products (CD19/CD22 dual targets, BCMA-targeting), BTK inhibitors in B-cell lymphomas, and total metabolic volume on PET as a predictive biomarker for treatment adaptation.

Frequently Asked Questions — dlbcl diffuse large b cell lymphoma Clinical Trials

How many clinical trials are currently recruiting for dlbcl diffuse large b cell lymphoma?
ClinicalMetric currently tracks 8 actively recruiting clinical trials for dlbcl diffuse large b cell lymphoma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 8. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for dlbcl diffuse large b cell lymphoma?
dlbcl diffuse large b cell lymphoma research spans Phase 2 (4 trials), Phase 3 (2 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a dlbcl diffuse large b cell lymphoma clinical trial?
Eligibility criteria for dlbcl diffuse large b cell lymphoma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 2
4
Phase 3
2
Top Sponsors
The First Affiliated Hospital of Xiamen University 3 trials
King Edward Medical University 1 trial
University Medical Center Goettingen 1 trial
Australasian Leukaemia and Lymphoma Group 1 trial
Stichting Hemato-Oncologie voor Volwassenen Nederland 1 trial

Recruiting Clinical Trials

NCT07739654 Phase 3
Recruiting
Modified DHAP Versus Standard DHAP in Relapsed/Refractory Diffused Large B-cell Lymphoma.
Enrollment
74 pts
Location
Pakistan
Sponsor
King Edward Medical University
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NCT06526065
Recruiting
Molecular Mechanisms in Malignant Lymphoma- Predict (MMML Predict)
Enrollment
500 pts
Location
Germany
Sponsor
University Medical Center Goet...
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NCT06151080 Phase 2
Recruiting
Lenalidomide Combined With G-CHOP in the Treatment of Newly Diagnosed DLBCL With FL
Enrollment
38 pts
Location
China
Sponsor
The First Affiliated Hospital ...
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NCT07778212
Recruiting
Orelabrutinib Combined With Pola-R-CHP as First-Line Treatment for Patients With Intermediate- to High-Risk DLBCL
Enrollment
30 pts
Location
China
Sponsor
The First Affiliated Hospital ...
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NCT06287398 Phase 2
Recruiting
Epcoritamab (Epcor)-Containing Combination Salvage Therapy Followed by ASCT & Epcor Consolidation in Patients With Relapsed LBCL
Enrollment
39 pts
Location
Australia
Sponsor
Australasian Leukaemia and Lym...
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NCT07749365 Phase 2
Recruiting
Hypofractionated Radiotherapy Plus GM-CSF, Pomalidomide and Glofitamab for Newly Diagnosed PCNS-DLBCL
Enrollment
53 pts
Location
China
Sponsor
The First Affiliated Hospital ...
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NCT06220032 Phase 3
Recruiting
Prevention of Anthracycline-Induced Cardiac Dysfunction With Dexrazoxane in Patients With Diffuse Large-B Cell Lymphoma
Enrollment
324 pts
Location
Netherlands
Sponsor
Stichting Hemato-Oncologie voo...
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NCT06919939 Phase 2
Recruiting
Epcoritamab in Combination With Loncastuximab Tesirine in Relapsed/Refractory Large B-cell Lymphoma
Enrollment
26 pts
Location
United States
Sponsor
University of Miami
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Related Conditions

follicular lymphoma (1) intermediate high risk (1) first line (1) high grade b cell lymphoma (1) high grade b cell lymphoma with myc and bcl2 or bcl6 rearrangements (1) dlbcl nos genetic subtypes (1) high grade b cell lymphoma not otherwise specified (1) follicular large cell lymphoma relapsed (1) follicular large cell lymphoma (1) pcnsl primary cns lymphoma (1) large b cell lymphoma (1) relapse (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology