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covid 19 vaccine

Total Trials
1
Recruiting Now
1
Trial Phases
Phase 1

COVID-19 trials proliferated rapidly during the pandemic and now encompass antiviral treatments, long COVID management, and ongoing vaccine refinements for new variants. The platform trial model — where multiple interventions share a single control arm — was pioneered at scale for COVID-19 (RECOVERY, ACTIV-3, SOLIDARITY) and has since been adopted across other disease areas.

Active trials address long COVID (fatigue, cognitive impairment, autonomic dysfunction), antiviral combinations for high-risk outpatients, mucosal vaccines for variant-resistant immunity, and mechanistic studies into post-COVID organ damage. Paxlovid rebound, nirmatrelvir resistance, and immunocompromised host management are current investigation areas.

Trial Phases
Phase 1
1
Top Sponsors
The Methodist Hospital Research Institute 1 trial
NCT06821100 Phase 1
Recruiting

Thymalfasin (Thymosin Alpha 1; Ta1) as an Enhancer of Vaccine Response Among Older Adults Receiving Booster Doses of COVID-19 Vaccine

Enrollment
75 pts
Location
United States
Sponsor
The Methodist Hospital Researc...
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology