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anterior cruciate ligament reconstruction

Total Trials
5
Recruiting Now
5
Trial Phases
Phase 4

ClinicalMetric tracks all active clinical trials for anterior cruciate ligament reconstruction sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — anterior cruciate ligament reconstruction Clinical Trials

How many clinical trials are currently recruiting for anterior cruciate ligament reconstruction?
ClinicalMetric currently tracks 5 actively recruiting clinical trials for anterior cruciate ligament reconstruction, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 5. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for anterior cruciate ligament reconstruction?
anterior cruciate ligament reconstruction research spans Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a anterior cruciate ligament reconstruction clinical trial?
Eligibility criteria for anterior cruciate ligament reconstruction trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 4
1
Top Sponsors
Hospital for Special Surgery, New York 1 trial
Zuyderland Medisch Centrum 1 trial
Marquette University 1 trial
University Ghent 1 trial
Yale University 1 trial

Recruiting Clinical Trials

NCT06590402 Phase 4
Recruiting

Anterior Femoral and Adductor Canal Nerve Blocks in Peds Knees

Enrollment
60 pts
Location
United States
Sponsor
Hospital for Special Surgery, ...
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NCT05972876
Recruiting

Graft Maturity After Blood Flow Restriction Training in ACL Reconstruction

Enrollment
46 pts
Location
Netherlands
Sponsor
Zuyderland Medisch Centrum
View Trial →
NCT06858293
Recruiting

Mental Imagery to Improve Quadriceps Strength Post Anterior Cruciate Ligament Reconstruction: a Feasibility Study

Enrollment
20 pts
Location
United States
Sponsor
Marquette University
View Trial →
NCT06206200
Recruiting

The Effects of Cognitive Dual-Tasking in Later Stages of Rehabilitation After ACL Reconstruction

Enrollment
80 pts
Location
Belgium
Sponsor
University Ghent
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NCT05012982
Recruiting

Immunometabolic Mechanisms of Blood Flow Restriction (BFR) Training After Anterior Cruciate Ligament Reconstruction

Enrollment
20 pts
Location
United States
Sponsor
Yale University
View Trial →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology