Medical Condition

acute lymphoblastic leukemia recurrent

Total Trials

1

Recruiting Now

1

Trial Phases

Various

Leukemia clinical trials cover acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), chronic myeloid leukemia (CML), and chronic lymphocytic leukemia (CLL) — distinct diseases with profoundly different biology and treatment approaches. AML research focuses on targeted agents for FLT3, IDH1/2, and TP53-mutated disease, while CLL trials explore fixed-duration venetoclax combinations that achieve treatment-free remissions.

Active trials investigate menin inhibitors for NPM1/KMT2A AML, magrolimab (anti-CD47) combinations, bispecific antibodies in relapsed ALL, and next-generation BTK inhibitors (pirtobrutinib) for ibrutinib-resistant CLL. MRD (minimal residual disease) negativity is emerging as a regulatory endpoint to accelerate approvals.

Top Sponsors

King Hussein Cancer Center 1 trial

Recruiting Clinical Trials

NCT07371403

Recruiting

MB-CART19.1 in Relapsed/Refractory Acute Lymphoblastic Leukemia

King Hussein Cancer Center

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