Medical Condition

acute exacerbation of asthma

Total Trials

1

Recruiting Now

1

Trial Phases

Various

Asthma clinical trials are increasingly stratified by phenotype — Type 2 high (eosinophilic, IgE-mediated) versus Type 2 low (neutrophilic or paucigranulocytic) — because this distinction predicts response to biologic therapies. The anti-IL-5, anti-IL-4/13, and anti-TSLP antibody classes have revolutionized severe asthma management, and trials now aim to achieve full remission rather than just symptom control.

Trials evaluate dupilumab combinations, tezepelumab (anti-TSLP) in Type 2 low asthma, itepekimab, biologic step-down strategies, and oral corticosteroid-sparing approaches. Digital inhalers with adherence monitoring are being validated as outcomes tools. Bronchial thermoplasty for severe non-biologic-responsive patients remains an active surgical comparator.

Top Sponsors

National University Hospital, Singapore 1 trial

Recruiting Clinical Trials

NCT07536035

Recruiting

Potential of Interface Care Models to Deliver More Appropriate Care to Patients With Acute Medical Illness

National University Hospital, ...

View Trial →

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