NCT07462091 Vagus Nerve-guided Laparoscopic Splenectomy and Azygoportal Disconnection
| NCT ID | NCT07462091 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Northern Jiangsu People's Hospital |
| Condition | Cirrhosis |
| Study Type | INTERVENTIONAL |
| Enrollment | 15 participants |
| Start Date | 2026-03-25 |
| Primary Completion | 2027-03-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 15 participants in total. It began in 2026-03-25 with a primary completion date of 2027-03-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aimed to evaluate the effectiveness and safety of vagus nerve-guided laparoscopic splenectomy and azygoportal disconnection, and to assess its impact on postoperative digestive complications and quality of life.
Eligibility Criteria
Inclusion Criteria: 1. A clinical, radiological or histologic diagnosis of cirrhosis of any etiology 2. Splenomegaly with secondary hypersplenism 3. Bleeding portal hypertension 4. No evidence of portal vein system thrombosis by ultrasound evaluation and angio-CT 5. Informed consent to participate in the study Exclusion Criteria: 1. Delayed gastric emptying 2. Diarrhea 3. Hepatocellular carcinoma or any other malignancy, 4. Hypercoagulable state other than the liver disease related 5. DRUGS- oral contraceptives, anticoagulation or anti-platelet drugs. 6. Child - Pugh C 7. Recent peptic ulcer disease 8. History of Hemorrhagic stroke 9. Pregnancy. 10. Uncontrolled Hypertension 11. Human immunodeficiency virus (HIV) infection
Contact & Investigator
Dou-Sheng Bai, MD
STUDY CHAIR
Clinical Medical College, Yangzhou University
Frequently Asked Questions
Who can join the NCT07462091 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Cirrhosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07462091 currently recruiting?
Yes, NCT07462091 is actively recruiting participants. Contact the research team at jgqing2003@hotmail.com for enrollment information.
Where is the NCT07462091 trial being conducted?
This trial is being conducted at Yangzhou, China, Yangzhou, China.
Who is sponsoring the NCT07462091 clinical trial?
NCT07462091 is sponsored by Northern Jiangsu People's Hospital. The principal investigator is Dou-Sheng Bai, MD at Clinical Medical College, Yangzhou University. The trial plans to enroll 15 participants.