NCT06610877 Ultrasound Neuromodulation in Essential Tremor
| NCT ID | NCT06610877 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of California, San Francisco |
| Condition | Essential Tremor |
| Study Type | INTERVENTIONAL |
| Enrollment | 60 participants |
| Start Date | 2024-10-01 |
| Primary Completion | 2027-03 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 60 participants in total. It began in 2024-10-01 with a primary completion date of 2027-03.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study is being done to test whether low-intensity focused ultrasound (LIFU) (low energy sound waves) cause temporary changes in brain activity and behavior when directed at particular parts of the brain. By targeting LIFU to the parts of the brain thought to be responsible for essential tremor (ET), and measuring any associated improvement in tremor, the investigators hope to show that LIFU can be a useful tool for studying the brain circuits responsible for tremor and other brain disorders.
Eligibility Criteria
Inclusion Criteria: * Patients with medically refractory tremor scheduled to undergo MR-guided high-intensity focused ultrasound (HIFU) thalamotomy to treat their tremor at UCSF. Exclusion Criteria: * Due to the logistical complexity of performing MRI in patients with MR-conditional pacemakers (need for device and patient monitoring), patients with pacemakers will be excluded from enrollment. All other patients undergoing HIFU thalamotomy for tremor will be eligible for enrollment.
Contact & Investigator
Leo Sugrue, MD, PhD
PRINCIPAL INVESTIGATOR
University of California, San Francisco
Frequently Asked Questions
Who can join the NCT06610877 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Essential Tremor. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06610877 currently recruiting?
Yes, NCT06610877 is actively recruiting participants. Contact the research team at leo.sugrue@ucsf.edu for enrollment information.
Where is the NCT06610877 trial being conducted?
This trial is being conducted at San Francisco, United States.
Who is sponsoring the NCT06610877 clinical trial?
NCT06610877 is sponsored by University of California, San Francisco. The principal investigator is Leo Sugrue, MD, PhD at University of California, San Francisco. The trial plans to enroll 60 participants.