NCT07391280 Strategy for EArly Recognition of Cancer, COPD & Heart Failure in the Emergency Department
| NCT ID | NCT07391280 |
| Status | Recruiting |
| Phase | — |
| Sponsor | NHS Greater Glasgow and Clyde |
| Condition | Cancer |
| Study Type | INTERVENTIONAL |
| Enrollment | 17,000 participants |
| Start Date | 2026-05-25 |
| Primary Completion | 2027-06 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 17,000 participants in total. It began in 2026-05-25 with a primary completion date of 2027-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
SEARCH-ED is a research study which is running in Emergency Department (ED) of the Queen Elizabeth University Hospital. The aim of the study is to find out if using a computer programme can help doctors diagnose heart and lung problems from chest x-rays. We want to compare how many people are diagnosed with heart or lung problems for the first time when doctors have access to the computer programme results, in comparison to when they don't.
Eligibility Criteria
Inclusion Criteria: Unconsented Use of Harrison CXR Algorithm in Emergency Department (ED): * Frontal Chest X-Ray (CXR) (AP or PA) acquired in the Queen Elizabeth University Hospital (QEUH) ED * Patients aged 18 or over * Appropriate meta data (DICOM) to allow for Harrison CXR processing and secondary capture report provision. Patient Focus Groups: * Aged 18 or over * Able to provide written, informed consent in English. Clinician Focus Groups: * Aged 18 or over * Able to provide written, informed consent in English. * Working as a doctor, advanced nurse practitioner or advanced clinical practitioner in ED, radiology or downstream medical specialties * For post-implementation focus groups only, must have at least 4 months experience of working with Harrison CXR algorithm. Diagnostic Clinic: * Patients without terminal illness or advanced frailty * Usual healthcare provider based in NHS GGC Exclusion Criteria: Applies to use of unconsented CXRs: \- Patient has requested that they are removed from the study, or has objected to the use of AI in their routine clinical care and this has been subsequently upheld by the health board. Applies to invitation to combined diagnostic clinic: * Patients not available to follow up, including patients i.e. whose the patient's usual care (or onward care following index admission) is out-with NHS GGC. * Patients who have been referred to palliative care for end-stage disease, or patients with severe frailty (i.e. bedbound) will not be invited to the combined diagnostic clinic For Patient and Clinician Focus Groups: * Unable to provide informed written consent in English * Aged \<18
Contact & Investigator
David J Lowe
PRINCIPAL INVESTIGATOR
University of Glasgow
Frequently Asked Questions
Who can join the NCT07391280 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07391280 currently recruiting?
Yes, NCT07391280 is actively recruiting participants. Contact the research team at clea.dutoit@nhs.scot for enrollment information.
Where is the NCT07391280 trial being conducted?
This trial is being conducted at Glasgow, United Kingdom.
Who is sponsoring the NCT07391280 clinical trial?
NCT07391280 is sponsored by NHS Greater Glasgow and Clyde. The principal investigator is David J Lowe at University of Glasgow. The trial plans to enroll 17,000 participants.
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