NCT07544823 Screening for Biomarkers of Osteoarthritis
| NCT ID | NCT07544823 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The First Affiliated Hospital of Xinxiang Medical College |
| Condition | Osteoarthritis (OA) |
| Study Type | OBSERVATIONAL |
| Enrollment | 300 participants |
| Start Date | 2026-04-20 |
| Primary Completion | 2026-12-30 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 300 participants in total. It began in 2026-04-20 with a primary completion date of 2026-12-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Osteoarthritis (OA) is the most prevalent degenerative joint disease worldwide, which causes pain, loss of joint function and declined quality of life, and ranks as the leading cause of disability among individuals aged over 60 years. In China, the number of patients with osteoarthritis is projected to exceed 200 million by 2044, resulting in a continuously growing demand for medical resources and escalating economic burden.Nevertheless, the lack of effective biomarkers for early diagnosis leads to advanced disease conditions at the time of initial medical consultation and delayed treatment. This project intends to collect blood samples from OA patients and suspected patients in the orthopedic outpatient department of a tertiary hospital. Diagnostic and differential diagnostic tests will be adopted to verify the clinical application value of previously reported candidate biomarkers, so as to screen out biomarkers with favorable validity and reliability. The research findings are expected to provide data support and theoretical basis for the early prevention, early diagnosis and individualized intervention of osteoarthritis.
Eligibility Criteria
Inclusion Criteria: 1. Aged between 40 and 70 years (inclusive); 2. Joint pain or stiffness lasting for no less than 3 months; 3. Voluntary participation with signed informed consent. Exclusion Criteria: 1. Combined with other severe joint diseases, such as rheumatoid arthritis, gout, etc.; 2. Suffering from severe systemic diseases, such as heart failure, malignant tumors and others; 3. Received joint surgery within the past 3 months or taking medications that may affect the progression of osteoarthritis; 4. Individuals with cognitive dysfunction who are unable to cooperate with the research procedures; 5. Failure to complete X-ray, MRI examination or follow-up visits as required.
Contact & Investigator
Wenjie Ren
STUDY CHAIR
The First Affiliated Hospital of Henan Medical University
Frequently Asked Questions
Who can join the NCT07544823 clinical trial?
This trial is open to participants of all sexes, aged 40 Years or older, up to 70 Years, studying Osteoarthritis (OA). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07544823 currently recruiting?
Yes, NCT07544823 is actively recruiting participants. Contact the research team at 157121431@qq.com for enrollment information.
Where is the NCT07544823 trial being conducted?
This trial is being conducted at Xinxiang, China.
Who is sponsoring the NCT07544823 clinical trial?
NCT07544823 is sponsored by The First Affiliated Hospital of Xinxiang Medical College. The principal investigator is Wenjie Ren at The First Affiliated Hospital of Henan Medical University. The trial plans to enroll 300 participants.