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Recruiting NCT05974995

NCT05974995 Robotic-assisted Versus Conventional Laparoscopic Surgery in Obese Patients With Early Endometrial Cancer

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Clinical Trial Summary
NCT ID NCT05974995
Status Recruiting
Phase
Sponsor Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Condition Endometrial Cancer
Study Type INTERVENTIONAL
Enrollment 566 participants
Start Date 2023-09-01
Primary Completion 2026-09-01

Eligibility & Interventions

Sex Female only
Min Age 18 Years
Max Age 75 Years
Study Type INTERVENTIONAL
Interventions
Robot-assisted surgeryLaparoscopic surgery

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 566 participants in total. It began in 2023-09-01 with a primary completion date of 2026-09-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Data across literature suggest that robotic surgery may offer benefit specifically in patient with morbid obesity with endometrial cancer, but to date no randomized trials have been conducted to confirm these observations. This randomized controlled multicentric trial aims to evaluate the most appropriate minimally invasive surgical approach in morbidly obese (BMI \>= 30) patients with endometrial carcinoma.

Eligibility Criteria

Inclusion Criteria: * BMI \>=30 * Age \> 18 * Histologically confirmed endometrioid endometrial cancer * Clinical early stage (stage I) * No contraindication for minimally invasive surgery * ASA\<4 * Written informed consent. Exclusion Criteria: * High probability of laparotomy related to uterine volume (US estimated weight \>250 g) * Concomitant pelvic disease, or anatomical characteristics of the patient * (Use of uterine manipulator) * Age \>75 years

Contact & Investigator

Central Contact

Francesco Fanfani, MD

✉ francesco.fanfani@policlinicogemelli.it

📞 0630153421

Principal Investigator

Francesco Fanfani, MD

PRINCIPAL INVESTIGATOR

Policlinico Gemelli IRCCS

Frequently Asked Questions

Who can join the NCT05974995 clinical trial?

This trial is open to female participants only, aged 18 Years or older, up to 75 Years, studying Endometrial Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05974995 currently recruiting?

Yes, NCT05974995 is actively recruiting participants. Contact the research team at francesco.fanfani@policlinicogemelli.it for enrollment information.

Where is the NCT05974995 trial being conducted?

This trial is being conducted at Rome, Italy.

Who is sponsoring the NCT05974995 clinical trial?

NCT05974995 is sponsored by Fondazione Policlinico Universitario Agostino Gemelli IRCCS. The principal investigator is Francesco Fanfani, MD at Policlinico Gemelli IRCCS. The trial plans to enroll 566 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology