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Recruiting NCT05661448

NCT05661448 Promoting Cognitive Health in Schizophrenia

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Clinical Trial Summary
NCT ID NCT05661448
Status Recruiting
Phase
Sponsor Douglas Mental Health University Institute
Condition Schizophrenia
Study Type INTERVENTIONAL
Enrollment 390 participants
Start Date 2023-04-15
Primary Completion 2029-08-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Cognitive remediationMetaCognitive Training

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 390 participants in total. It began in 2023-04-15 with a primary completion date of 2029-08-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this clinical trial is to effectively implement virtually-delivered interventions in mental health institutions nationwide to improve the cognitive health of individuals living with schizophrenia. The main objectives are: * To determine the clinical effectiveness of two virtual cognitive health interventions (i.e., Action-Based Cognitive Remediation or MetaCognitive Training). * To evaluate our implementation strategy involving the virtual delivery of cognitive health interventions combined with a digital learning platform to train mental health practitioners. Participants will be assessed for the severity of symptoms, cognitive performance, and overall functioning before and after receiving the intervention. Qualitative interviews will also be conducted with participants and therapists to evaluate the implementation strategies.

Eligibility Criteria

Inclusion Criteria: * Diagnosis of affective or non-affective psychosis or related disorder; * Follow-up and treatment by a clinician at one of the services mentioned above; * Participants symptomatically stable and capable of using the online platforms and participating in intervention groups, as judged by their primary clinicians (i.e., psychiatrist, case manager); * Participants must have access to a private space (i.e., a room where the participant can be alone) to ensure confidentiality for the group; * Participants must be able to nominate an emergency contact and to agree to allow researchers to contact their clinician and/or emergency services in the event of an emergency during study procedures. Exclusion Criteria: * Intellectual disability; * Hospitalization at the time of recruitment; * Inability to speak or read English or French; * High suicide risk as per evaluation.

Contact & Investigator

Central Contact

Karyne Anselmo

✉ karyne.anselmo@douglas.mcgill.ca

📞 (514) 761-6131

Principal Investigator

Martin Lepage

PRINCIPAL INVESTIGATOR

Douglas Mental Health University Institute

Frequently Asked Questions

Who can join the NCT05661448 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Schizophrenia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05661448 currently recruiting?

Yes, NCT05661448 is actively recruiting participants. Contact the research team at karyne.anselmo@douglas.mcgill.ca for enrollment information.

Where is the NCT05661448 trial being conducted?

This trial is being conducted at Vancouver, Canada, Kingston, Canada, Ottawa, Canada, Toronto, Canada and 1 additional location.

Who is sponsoring the NCT05661448 clinical trial?

NCT05661448 is sponsored by Douglas Mental Health University Institute. The principal investigator is Martin Lepage at Douglas Mental Health University Institute. The trial plans to enroll 390 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology