NCT07453992 Postoperative Rotational Dynamics of Three Toric Intraocular Lens Designs
| NCT ID | NCT07453992 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Jin Yang |
| Condition | Cataract |
| Study Type | INTERVENTIONAL |
| Enrollment | 400 participants |
| Start Date | 2025-01-01 |
| Primary Completion | 2026-10-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 400 participants in total. It began in 2025-01-01 with a primary completion date of 2026-10-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This prospective comparative cohort study evaluates and compares postoperative rotational stability and time-course dynamics of three commercially available toric intraocular lenses (TECNIS Toric II \[ZCU\], AcrySof IQ Toric, and AT TORBI 709M) after phacoemulsification cataract surgery. Rotation is quantified by registering postoperative retroillumination photographs to the end-of-surgery baseline using iris/scleral landmarks, with follow-up at postoperative day 1, day 3, week 1, week 2, month 1, and month 3. Associations between rotational outcomes and ocular biometric parameters are analyzed using linear mixed-effects models to inform individualized IOL selection and perioperative management.
Eligibility Criteria
Inclusion Criteria: * Adults aged 18 years or older with age-related cataract scheduled for phacoemulsification cataract surgery. * Presence of regular corneal astigmatism requiring toric intraocular lens implantation. * Eligible for implantation of one of the three study toric intraocular lenses based on preoperative evaluation. * Ability to understand the study procedures and provide written informed consent. Exclusion Criteria: * History of prior ocular surgery in the study eye. * History of ocular trauma in the study eye. * Irregular corneal astigmatism or corneal pathology affecting reliable biometric measurement. * Intraoperative complications, including anterior capsular tear or posterior capsular rupture. * Inadequate pupillary dilation during surgery or postoperative examinations. * Evidence of zonular weakness, zonular dialysis, or lens subluxation. * Active ocular infection or inflammation. * Any other ocular or systemic condition judged by the investigator to potentially affect intraocular lens stability or study outcomes.
Contact & Investigator
Jin Yang
PRINCIPAL INVESTIGATOR
Fudan University
Frequently Asked Questions
Who can join the NCT07453992 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Cataract. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07453992 currently recruiting?
Yes, NCT07453992 is actively recruiting participants. Contact the research team at 1532483480@qq.com for enrollment information.
Where is the NCT07453992 trial being conducted?
This trial is being conducted at Shanghai, China.
Who is sponsoring the NCT07453992 clinical trial?
NCT07453992 is sponsored by Jin Yang. The principal investigator is Jin Yang at Fudan University. The trial plans to enroll 400 participants.