NCT05277025 Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
| NCT ID | NCT05277025 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Florida |
| Condition | Fibromyalgia |
| Study Type | OBSERVATIONAL |
| Enrollment | 150 participants |
| Start Date | 2022-03-22 |
| Primary Completion | 2027-02-28 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 150 participants in total. It began in 2022-03-22 with a primary completion date of 2027-02-28.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Fibromyalgia (FM) is a chronic musculoskeletal pain disorder that afflicts up to 4% of the general population. The evaluation of pain mechanisms in FM has shown predominant central abnormalities and therefore has been designated as nociplastic pain syndrome. Rheumatoid arthritis (RA) is characterized by polyarthritis and pain from inflamed tissues, consistent with nociceptive pain. FM and RA patients may utilize overlapping pain mechanisms resulting in nociceptive and nociplastic pain.
Eligibility Criteria
Inclusion Criteria: * Ages 18-70 * Fulfills the 1990 and 2011 American College of Rheumatology Criteria for FM * Fulfills the 2010 ACR-EULAR classification criteria for RA * Healthy volunteers: No significant pain/fatigue/depression/anxiety. Exclusion Criteria: * Diabetes * Cancer * Advanced liver, kidney or cardiovascular disease * Neuropathic pain
Contact & Investigator
Roland Staud, M.D.
PRINCIPAL INVESTIGATOR
University of Florida
Frequently Asked Questions
Who can join the NCT05277025 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Fibromyalgia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05277025 currently recruiting?
Yes, NCT05277025 is actively recruiting participants. Contact the research team at staudr@ufl.edu for enrollment information.
Where is the NCT05277025 trial being conducted?
This trial is being conducted at Gainesville, United States.
Who is sponsoring the NCT05277025 clinical trial?
NCT05277025 is sponsored by University of Florida. The principal investigator is Roland Staud, M.D. at University of Florida. The trial plans to enroll 150 participants.
Related Trials
Related Intelligence Guides
In-depth guides covering this condition's trials, eligibility, and what to expect.