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Recruiting NCT05277714

NCT05277714 Neurofeedback Based on Near-infrared Spectroscopy as a Therapy for Food Addiction in Obese Subjects.

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Clinical Trial Summary
NCT ID NCT05277714
Status Recruiting
Phase
Sponsor Rennes University Hospital
Condition Obesity
Study Type INTERVENTIONAL
Enrollment 50 participants
Start Date 2022-05-25
Primary Completion 2026-05

Eligibility & Interventions

Sex Female only
Min Age 18 Years
Max Age 55 Years
Study Type INTERVENTIONAL
All Conditions
Interventions
ShamNF

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 50 participants in total. It began in 2022-05-25 with a primary completion date of 2026-05.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The hypothesis is that the increase in dlPFC brain activity via near-infrared spectroscopy-based Neurofeedback (fNIRS-based NF) training based on near-infrared spectroscopy would allow an improvement of the eating behavior, thus promoting a long-term weight loss in obese subjects. Patients will be trained during a month with 8 NF sessions and results based on clinical data and different questionnaires results will be compared between inclusion and 3 months later

Eligibility Criteria

Inclusion Criteria: * Eligible for obesity surgery according to the 2009 French High Authority on Health (HAS) criteria (BMI ≥40 or BMI ≥35 with comorbidities) * Right-handed * Presenting a food addiction determined by the YFAS 2.0 questionnaire ; * Affiliated to a social security system; * Having given free and informed consent in writing. Exclusion Criteria: * Psychotic psychiatric disorders (schizophrenic disorders and bipolar disorders); * Psychotropic drugs, except antidepressants stabilized for at least 3 weeks and benzodiazepines * Addiction to alcohol or other psychoactive substances (except tobacco); * History of bariatric surgery; * Current treatment in the nutrition unit; * Insufficient command of French; * Pregnant or breast-feeding woman; * Persons of legal age under legal protection (safeguard of justice, curatorship, guardianship), persons deprived of liberty. * Contraindications to fMRI * Inability to perform the fNIRS procedure due to blockage or attenuation of the light at the capillary level

Contact & Investigator

Central Contact

Marie-Laure GERVAIS

✉ marie-laure.gervais@chu-rennes.fr

📞 0618454735

Frequently Asked Questions

Who can join the NCT05277714 clinical trial?

This trial is open to female participants only, aged 18 Years or older, up to 55 Years, studying Obesity. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05277714 currently recruiting?

Yes, NCT05277714 is actively recruiting participants. Contact the research team at marie-laure.gervais@chu-rennes.fr for enrollment information.

Where is the NCT05277714 trial being conducted?

This trial is being conducted at Rennes, France.

Who is sponsoring the NCT05277714 clinical trial?

NCT05277714 is sponsored by Rennes University Hospital. The trial plans to enroll 50 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology