| NCT ID | NCT06625762 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Nantes University Hospital |
| Condition | Obesity |
| Study Type | INTERVENTIONAL |
| Enrollment | 300 participants |
| Start Date | 2026-03-23 |
| Primary Completion | 2028-03-23 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 300 participants in total. It began in 2026-03-23 with a primary completion date of 2028-03-23.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
While current research suggests that inflammation of adipose tissue in obesity is linked to accelerated aging, it has yet to be determined in humans how this could enhance preventative and personalized medicine for obese individuals. The NBC study aims to investigate : 1. Whether bariatric surgery is associated with changes in biological age 2. If bariatric surgery alters adipocyte dysfunction, the microbiota and biological rhythms 3. Whether changes in adipocyte dysfunction, microbiota and biological rhythms are linked to changes in biological age. To achieve this, establishing a biocollection before, during and after bariatric surgery will be crucial in addressing these questions
Eligibility Criteria
Inclusion Criteria : Individuals selected for bariatric surgery (starting the BC pathway within the Nantes University Hospital bariatric unit). Inclusion criteria are those of the Bariatric Surgery program. * male or female, adult over 18 years of age * BMI ≥ 35 kg/m2 with complication(s) or ≥ 40 kg/m2 with or without complication (the list of eligible complications is referenced in HAS 2024 recommendations). In the event of a change in access to bariatric surgery, this threshold could be revised without any substantial change to the protocol. * having consented to their participation in the cohort * participant affiliated to or benefiting from a social security scheme Exclusion Criteria : * Persons protected by law (guardianship or trusteeship) or deprived of their freedom, * Pregnant women (contraindication to CB) or nursing mothers.
Contact & Investigator
David JACOBI, PU-PH
PRINCIPAL INVESTIGATOR
Nantes University Hospital
Frequently Asked Questions
Who can join the NCT06625762 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Obesity. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06625762 currently recruiting?
Yes, NCT06625762 is actively recruiting participants. Contact the research team at david.jacobi@chu-nantes.fr for enrollment information.
Where is the NCT06625762 trial being conducted?
This trial is being conducted at Nantes, France.
Who is sponsoring the NCT06625762 clinical trial?
NCT06625762 is sponsored by Nantes University Hospital. The principal investigator is David JACOBI, PU-PH at Nantes University Hospital. The trial plans to enroll 300 participants.
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