NCT03999138 MRI Assessment of Pulmonary Edema in Acute Heart Failure
| NCT ID | NCT03999138 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Alberta |
| Condition | Acute Heart Failure |
| Study Type | OBSERVATIONAL |
| Enrollment | 300 participants |
| Start Date | 2019-01-02 |
| Primary Completion | 2027-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 300 participants in total. It began in 2019-01-02 with a primary completion date of 2027-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Researchers are testing a more accurate way to measure how much fluid is in the lungs (also called pulmonary edema, or "increased lung water") in people with Heart Failure (HF) using MRI (Magnetic Resonance Imaging). There is little known about the exact level of lung water in patients with AHF or how these levels change from the time of hospital admission to discharge. The purpose of this research study is to measure the lung water in patients hospitalized for HF, to determine the change in lung water over the course of hospitalization and treatment, and to find out if lung water levels can predict if patients are higher or lower risk for returning to the hospital or dying from heart failure.
Eligibility Criteria
Inclusion Criteria: * 18 years of age or older and willing/able to provide informed consent * patients being treated for acute heart failure (including those patients with both reduced and preserved ejection fraction) * patients receiving medical therapy for pulmonary edema by current standard of care (including oral or IV diuretics) * patients identified within 48 hours of initiation of medical therapy for pulmonary edema, defined as the time of first diuretic (IV or PO) or escalation of existing diuretic therapy administered within the ED or hospital Exclusion Criteria: * contraindication to MRI * patient too critically ill/unstable as per the clinical care team for transport to MRI scanner within the required scanning window * moderate to severe dementia
Contact & Investigator
Frequently Asked Questions
Who can join the NCT03999138 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Acute Heart Failure. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT03999138 currently recruiting?
Yes, NCT03999138 is actively recruiting participants. Contact the research team at DPaterson@ottawaheart.ca for enrollment information.
Where is the NCT03999138 trial being conducted?
This trial is being conducted at Edmonton, Canada, Ottawa, Canada.
Who is sponsoring the NCT03999138 clinical trial?
NCT03999138 is sponsored by University of Alberta. The trial plans to enroll 300 participants.
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