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Recruiting NCT05837221

NCT05837221 Microbiome in Head and Neck Squamous Cell Carcinoma

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Clinical Trial Summary
NCT ID NCT05837221
Status Recruiting
Phase
Sponsor University of Colorado, Denver
Condition Head and Neck Cancer
Study Type OBSERVATIONAL
Enrollment 60 participants
Start Date 2025-05-23
Primary Completion 2026-11

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 100 Years
Study Type OBSERVATIONAL
Interventions
Metagenomic sequencingMetabolic analysis

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 60 participants in total. It began in 2025-05-23 with a primary completion date of 2026-11.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study aims to determine whether dysbiosis actively contributes to HNSCC and if so, the underlying molecular mechanisms.

Eligibility Criteria

Inclusion Criteria: 1. Subjects equal to or above the age of 18. 2. Patients who are seen and evaluated by a provider within the adult Otolaryngology clinic at the University of Colorado Health. 3. Patients that present with a diagnosis of OSCC. 4. An equal number of age-matched patients who are visiting the clinic for reasons other than OSCC diagnoses, as the control group. 5. Ability to understand and willingness to sign a written informed consent document Exclusion Criteria: 1. Subjects under the age of 18 or over the age of 100 2. Subjects unwilling to particiapte

Contact & Investigator

Central Contact

Yosr Doghri

✉ yosr.doghri@cuanschutz.edu

📞 (303) 724-6550

Principal Investigator

Shi-Long E Lu, MD, PhD

PRINCIPAL INVESTIGATOR

University of Colorado, Denver

Frequently Asked Questions

Who can join the NCT05837221 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 100 Years, studying Head and Neck Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05837221 currently recruiting?

Yes, NCT05837221 is actively recruiting participants. Contact the research team at yosr.doghri@cuanschutz.edu for enrollment information.

Where is the NCT05837221 trial being conducted?

This trial is being conducted at Aurora, United States.

Who is sponsoring the NCT05837221 clinical trial?

NCT05837221 is sponsored by University of Colorado, Denver. The principal investigator is Shi-Long E Lu, MD, PhD at University of Colorado, Denver. The trial plans to enroll 60 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology