NCT06496425 Inspiring Seniors Towards Exercise Promotion to Protect Cognition
| NCT ID | NCT06496425 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Emory University |
| Condition | Alzheimer Disease |
| Study Type | INTERVENTIONAL |
| Enrollment | 80 participants |
| Start Date | 2024-05-15 |
| Primary Completion | 2026-10 |
Eligibility & Interventions
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 80 participants in total. It began in 2024-05-15 with a primary completion date of 2026-10.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to test the benefits of beat-accented music stimulation (BMS) for behavioral changes of physical activity (PA) in older adults with subjective memory complaints. Specific Aims are to determine (1) whether BMS beneficially influences PA behaviors and psychological responses to PA in older adults for 6 months, and (2) whether exercising with BMS differently influences physical and cognitive functioning as well as quality of life in older adults. To test the effects of BMS on PA, participants will be randomly assigned to an exercise intervention that either includes BMS or does not include BMS. Participants will attend a supervised group strength training (ST) (30 minutes per day) and aerobic exercise (AE) (30-50 minutes per day) session for 3 days per week for the first 2 months, 1 day per week for the next 2 months (while encouraging participants to independently perform both AE and ST on other days), and independently for the final 2 months (always with a goal of performing \>150minutes per week AE and 3 days per week of ST for 30 minutes per day).
Eligibility Criteria
Inclusion Criteria: * Adults at least 65 years old. * Ambulatory/capable of walking without pain or the use of assisted walking devices. * Able to speak and read English. * Healthy enough to exercise at moderate intensity with or without medical clearance by a primary care physician. * Living in the community for the duration of the study. * Having a reliable means of transportation. * Having a safe place at home or a residential area (at least 6 feet by 6 feet of open space) for unsupervised exercise training. * Being low-active (\< 60 min/week of moderate-intensity aerobic exercise and no strength training for the last 3 months). * Having SCC, defined by the Cognitive Change Index (CCI) ≥ 15. Exclusion Criteria: * Concurrent diagnosis of neurological disorder (e.g., dementia, Parkinson's disease, multiple sclerosis, stroke, etc.). * Known exercise contraindications (uncontrolled hypertension, joint problems, diabetes, metabolic conditions etc.). * Current cancer treatment. * Stroke or neural impairment in the past 6 months. * Hip/knee/spinal fracture or surgery in the past 6 months. * Unable or unwilling to attend intervention classes. * Currently participating in any other physical activity or fitness-related research study. * Use of medication for cognitive impairment. * Regularly drink \> 14 alcoholic beverages a week or current illicit drug use. * Meet the threshold for cognitive impairment. * Meet the threshold for clinical depression. * Uncorrected hearing or visual impairments. * Unable to understand the study procedures. * One of the household members is participating in this study.
Contact & Investigator
Kyoung Shin Park, PhD
PRINCIPAL INVESTIGATOR
Emory University
Frequently Asked Questions
Who can join the NCT06496425 clinical trial?
This trial is open to participants of all sexes, aged 65 Years or older, studying Alzheimer Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06496425 currently recruiting?
Yes, NCT06496425 is actively recruiting participants. Contact the research team at istep@emory.edu for enrollment information.
Where is the NCT06496425 trial being conducted?
This trial is being conducted at Atlanta, United States, Greensboro, United States.
Who is sponsoring the NCT06496425 clinical trial?
NCT06496425 is sponsored by Emory University. The principal investigator is Kyoung Shin Park, PhD at Emory University. The trial plans to enroll 80 participants.
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