NCT07456956 HIIT vs MCIT for Stroke-Related Sarcopenia in Ischemic Stroke
| NCT ID | NCT07456956 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Fenerbahce University |
| Condition | Stroke, Ischemic |
| Study Type | INTERVENTIONAL |
| Enrollment | 32 participants |
| Start Date | 2026-03-02 |
| Primary Completion | 2027-04-06 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 32 participants in total. It began in 2026-03-02 with a primary completion date of 2027-04-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The aim of this study is to investigate the effect of post-stroke sarcopenia on prognosis and clinical outcomes in patients with ischemic stroke and to compare the effects of High Intensity Interval Training (HIIT) and Moderate Intensity Continuous Training (MCIT) exercise programs on muscle mass, as well as on functional capacity, quality of life, and clinical outcomes.
Eligibility Criteria
Inclusion Criteria: * First-ever stroke. * Age 18 years or older. * Diagnosis of ischemic stroke. * Stroke duration between 1-6 months (subacute phase). * Modified Rankin Scale score \< 3. * Mini-Mental State Examination (MMSE) score ≥ 24. * Brunnstrom lower extremity motor stage between Stage III-V. * Lower extremity functional capacity sufficient to allow exercise participation (able to ambulate at least with an assistive device). * Lower extremity spasticity ≤ 2 according to the Modified Ashworth Scale. * Independent sitting balance (able to sit unsupported for at least 30 seconds). * Presence of sufficient voluntary active movement in the lower extremity to permit exercise application. * Ability to communicate. * Willingness to participate in the study and provision of written informed consent. Exclusion Criteria: * Presence of hemispatial neglect. * History of recurrent stroke. * Presence of a psychiatric disorder. * Presence of orthopedic, neurological, or cardiopulmonary conditions that would contraindicate the planned exercise protocols.
Contact & Investigator
Sümeyye Akçay, Asst. Prof.
PRINCIPAL INVESTIGATOR
Fenerbahçe University
Frequently Asked Questions
Who can join the NCT07456956 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 80 Years, studying Stroke, Ischemic. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07456956 currently recruiting?
Yes, NCT07456956 is actively recruiting participants. Contact the research team at smyye.akcy@gmail.com for enrollment information.
Where is the NCT07456956 trial being conducted?
This trial is being conducted at Istanbul, Turkey (Türkiye).
Who is sponsoring the NCT07456956 clinical trial?
NCT07456956 is sponsored by Fenerbahce University. The principal investigator is Sümeyye Akçay, Asst. Prof. at Fenerbahçe University. The trial plans to enroll 32 participants.
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