| NCT ID | NCT07487090 |
| Status | Recruiting |
| Phase | Phase 2 |
| Sponsor | Arkansas Colleges of Health Education |
| Condition | Obesity |
| Study Type | INTERVENTIONAL |
| Enrollment | 40 participants |
| Start Date | 2026-01-05 |
| Primary Completion | 2027-07 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
In Phase 2, researchers evaluate early signs of effectiveness. You may be randomized to receive the active treatment or a comparator. Monitoring continues closely.
This trial targets 40 participants in total. It began in 2026-01-05 with a primary completion date of 2027-07.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Although many medications exist for both heart disease and obesity, cost, lack of access for all people, side effects and the desire for a more natural solution have left many people seeking lifestyle treatments such as exercise. Scientists know that exercise is highly beneficial for heart health. When exercise also produces weight loss, these benefits are much improved. Although using exercise to treat or prevent heart disease / obesity is recommended, not all people respond well. Some see significant weight loss and health improvements while others see little changes. For these reasons, new strategies surrounding the use and design of an exercise program are needed. One such strategy could be performing aerobic exercise before breakfast (fasted exercise). When exercising fasted, food/energy stores are low, and one relies on stored body fat for energy. This may help heart health and weight loss. This has never been tested in a program long enough to see such changes. This study will, for the first time, assess the effects of a 16-week aerobic exercise program performed fasted compared to after eating. Outcomes will include blood fats, blood pressure, fat-burning abilities and weight loss. Starting an exercise program can also make people to eat more. This limits the success of exercise. The study will also evaluate ways fasted exercise could change eating, as it possible that fasted exercise could also cause people to eat more, which would limit weight loss and health improvements.
Eligibility Criteria
Inclusion Criteria: * Aged 18-59 * BMI 25-45 * Healthy enough to exercise Exclusion Criteria: * Taking medications or supplements that are known to influence energy expenditure, * Currently exercising more than once per week * Currently dieting for weight loss * Currently taking weight loss drugs * Have had a previous weight loss surgery * Currently diagnosed with Diabetes * Currently diagnosed with heart disease (Heart failure, uncontrolled hypertension, uncontrolled hypercholesterolemia, Coronary heart disease)
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07487090 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 59 Years, studying Obesity. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
What phase is the NCT07487090 trial and what does that mean for participants?
Phase 2 trials evaluate whether the treatment shows signs of effectiveness while continuing to monitor safety. More participants are enrolled than in Phase 1 to help refine the treatment protocol.
Is NCT07487090 currently recruiting?
Yes, NCT07487090 is actively recruiting participants. Contact the research team at kyle.flack@achehealth.edu for enrollment information.
Where is the NCT07487090 trial being conducted?
This trial is being conducted at Fort Smith, United States.
Who is sponsoring the NCT07487090 clinical trial?
NCT07487090 is sponsored by Arkansas Colleges of Health Education. The trial plans to enroll 40 participants.
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