NCT06285708 Enhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD
| NCT ID | NCT06285708 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Ohio State University |
| Condition | PTSD |
| Study Type | INTERVENTIONAL |
| Enrollment | 100 participants |
| Start Date | 2024-02-26 |
| Primary Completion | 2026-05 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 100 participants in total. It began in 2024-02-26 with a primary completion date of 2026-05.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The long-term goal of this study is to reduce suicidal thoughts and behaviors among treatment-seeking individuals who also have posttraumatic stress disorder (PTSD). Prolonged exposure (PE) and crisis response plan (CRP) have demonstrated empirical support for reducing suicide attempts as compared to treatment as usual. However, no studies to date have assessed their effectiveness when used in combination. In light of this knowledge gap, the primary objective of this study will be to test the effectiveness of PE augmented with CRP as compared to PE with care as usual (self-guided treatment plan), an active comparator, for the reduction of suicide ideations and attempts for individuals with comorbid PTSD.
Eligibility Criteria
Inclusion Criteria: * Current diagnosis of PTSD or subthreshold PTSD; ability to speak and understand the English language; and ability to complete the informed consent process. Exclusion Criteria: * Substance use disorder requiring medical management; imminent suicide risk warranting inpatient hospitalization or suicide-focused treatment; and impaired mental status that precludes the ability to provide informed consent (e.g., intoxication, psychosis, mania).
Contact & Investigator
Jaryd Hiser, Ph.D.
PRINCIPAL INVESTIGATOR
Assistant Professor
Frequently Asked Questions
Who can join the NCT06285708 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying PTSD. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06285708 currently recruiting?
Yes, NCT06285708 is actively recruiting participants. Contact the research team at jaryd.hiser@osumc.edu for enrollment information.
Where is the NCT06285708 trial being conducted?
This trial is being conducted at Columbus, United States.
Who is sponsoring the NCT06285708 clinical trial?
NCT06285708 is sponsored by Ohio State University. The principal investigator is Jaryd Hiser, Ph.D. at Assistant Professor. The trial plans to enroll 100 participants.
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