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Recruiting NCT07257744

NCT07257744 Comparison of IV Analgesia, Thoracic Epidural Analgesia, and ESP Block for Chronic Pain After Open Heart Surgery

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Clinical Trial Summary
NCT ID NCT07257744
Status Recruiting
Phase
Sponsor Karadeniz Technical University
Condition Chronic Postoperative Pain
Study Type OBSERVATIONAL
Enrollment 90 participants
Start Date 2025-02-15
Primary Completion 2025-12-20

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 85 Years
Study Type OBSERVATIONAL
Interventions
Intravenous AnalgesiaThoracic Epidural Analgesia (TEA)Erector Spinae Plane Block (ESPB)

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 90 participants in total. It began in 2025-02-15 with a primary completion date of 2025-12-20.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This prospective observational study aims to compare three routinely used postoperative analgesia techniques in patients undergoing open heart surgery: intravenous analgesia, thoracic epidural analgesia (TEA), and bilateral erector spinae plane block (ESPB). The primary objective is to evaluate the impact of these analgesia modalities on the development of chronic postoperative pain at 3 months. Secondary objectives include assessing postoperative acute pain scores, additional analgesic requirements, extubation time, mobilization time, intensive care unit stay, hospital stay, respiratory complications, and the relationship between acute and chronic pain. No intervention is assigned by protocol, and all analgesia methods are applied as part of routine clinical practice.

Eligibility Criteria

Inclusion Criteria: * Adults aged 18 to 85 years * Classified as ASA physical status I-III * Scheduled to undergo open heart surgery with median sternotomy * BMI \< 35 kg/m² * Able to understand and provide written informed consent * Eligible to receive any of the routine analgesia methods (intravenous analgesia, thoracic epidural analgesia, or erector spinae plane block) Exclusion Criteria: * Age \< 18 or \> 85 years * BMI ≥ 35 kg/m² * Coagulation disorders * Infection at the intervention site * Known allergy to local anesthetics or induction agents * Psychiatric disorders limiting cooperation * Use of chronic pain medications, antidepressants, corticosteroids, antiepileptics, or routine analgesics * Inability to cooperate, communicate, or follow commands * Physical or verbal performance impairment * Previous open heart surgery

Contact & Investigator

Central Contact

Ali AKDOGAN, MD

✉ draliakdogan@yahoo.com

📞 +905322605414

Frequently Asked Questions

Who can join the NCT07257744 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 85 Years, studying Chronic Postoperative Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07257744 currently recruiting?

Yes, NCT07257744 is actively recruiting participants. Contact the research team at draliakdogan@yahoo.com for enrollment information.

Where is the NCT07257744 trial being conducted?

This trial is being conducted at Trabzon, Turkey (Türkiye).

Who is sponsoring the NCT07257744 clinical trial?

NCT07257744 is sponsored by Karadeniz Technical University. The trial plans to enroll 90 participants.

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology