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Recruiting NCT07296250

NCT07296250 Circulating Tumor Cell Counts in Postoperative ENE-Positive Oral Cavity Cancer Patients After Adjuvant CCRT

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Clinical Trial Summary
NCT ID NCT07296250
Status Recruiting
Phase
Sponsor Chang Gung Memorial Hospital
Condition Head and Neck Cancer
Study Type INTERVENTIONAL
Enrollment 100 participants
Start Date 2025-08-01
Primary Completion 2026-07-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Months
Max Age 90 Years
Study Type INTERVENTIONAL
Interventions
low-dose oral chemotherapy

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 100 participants in total. It began in 2025-08-01 with a primary completion date of 2026-07-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The aim 1 of this trial is the development of the Circulating tumor cells (CTCs) definition of oral cancer minimal residual disease (MRD), and aim 2 is a prospective trial of oral cancer treatment. If this trial is successful, it is expected that it may be able to provide a standard diagnostic tool (MRD in Oral Cavity Squamous Cell Carcinoma (OCSCC)) and treatment mode (extended adjuvant chemotherapy with low-dose oral chemotherapy). The survival rate of patients will be improved.

Eligibility Criteria

Inclusion Criteria: Participants with Cancer: 1. Aged between 18 and 90 years. 2. Histologically confirmed diagnosis of head and neck squamous cell carcinoma (HNSCC). 3. Completed surgical treatment and identified as having high-risk factors, followed by concurrent chemoradiotherapy. 4. Willing to continue follow-up visits at the hospital after completion of treatment. Exclusion Criteria: 1. Presence of psychiatric disorders. 2. Deemed unsuitable for participation by the attending physician. 3. Unwilling to participate in the study.

Contact & Investigator

Central Contact

ChunTa Liao, PhD

✉ liaoct@cgmh.org.tw

📞 0975360141

Principal Investigator

ChunTa Liao, PhD

PRINCIPAL INVESTIGATOR

Division of Otolaryngology, Chang Gung Memorial Hospital

Frequently Asked Questions

Who can join the NCT07296250 clinical trial?

This trial is open to participants of all sexes, aged 18 Months or older, up to 90 Years, studying Head and Neck Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07296250 currently recruiting?

Yes, NCT07296250 is actively recruiting participants. Contact the research team at liaoct@cgmh.org.tw for enrollment information.

Where is the NCT07296250 trial being conducted?

This trial is being conducted at Taoyuan City, Taiwan.

Who is sponsoring the NCT07296250 clinical trial?

NCT07296250 is sponsored by Chang Gung Memorial Hospital. The principal investigator is ChunTa Liao, PhD at Division of Otolaryngology, Chang Gung Memorial Hospital. The trial plans to enroll 100 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology