| NCT ID | NCT04440761 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Queen Mary University of London |
| Condition | Myocardial Infarction |
| Study Type | OBSERVATIONAL |
| Enrollment | 3,000 participants |
| Start Date | 2020-07-01 |
| Primary Completion | 2026-09-16 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 3,000 participants in total. It began in 2020-07-01 with a primary completion date of 2026-09-16.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The last 15 years the introduction of primary angioplasty has radically improved outcomes for acute myocardial infarction (AMI). However, the system wide availability of prompt investigation has revealed an important group of patients where progress has stalled, the diagnosis is unclear and therapeutic approaches are uncertain. Myocardial infarction with non-obstructive coronary arteries (MINOCA) is found in 1 - 13% of all patients with a clinical diagnosis of AMI. These patients present a therapeutic predicament since coronary revascularization is not appropriate. Guidelines do not exist for their management - yet the condition is not benign - the 12-month prognosis, although better than obstructive coronary artery disease patients is still guarded with recent data suggesting many questions remain unanswered.
Eligibility Criteria
Inclusion Criteria: * Both male and female patients ≥16 years of age will be included * All patients will have a diagnosis MINOCA. Any patient who does not have a clear cause of troponin rise Exclusion Criteria: * Patients \<16 years will not be included in this study.
Contact & Investigator
Daniel Jones, MBBS, PhD
PRINCIPAL INVESTIGATOR
Queen Mary University of London
Frequently Asked Questions
Who can join the NCT04440761 clinical trial?
This trial is open to participants of all sexes, aged 16 Years or older, studying Myocardial Infarction. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04440761 currently recruiting?
Yes, NCT04440761 is actively recruiting participants. Contact the research team at dan.jones8@nhs.net for enrollment information.
Where is the NCT04440761 trial being conducted?
This trial is being conducted at London, United Kingdom.
Who is sponsoring the NCT04440761 clinical trial?
NCT04440761 is sponsored by Queen Mary University of London. The principal investigator is Daniel Jones, MBBS, PhD at Queen Mary University of London. The trial plans to enroll 3,000 participants.