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Recruiting Phase 1, Phase 2 NCT06239298

NCT06239298 A Study of ZG005 Combined With Donafenib in Patients With Advanced Solid Tumor

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Clinical Trial Summary
NCT ID NCT06239298
Status Recruiting
Phase Phase 1, Phase 2
Sponsor Suzhou Zelgen Biopharmaceuticals Co.,Ltd
Condition Solid Tumor
Study Type INTERVENTIONAL
Enrollment 130 participants
Start Date 2024-05-10
Primary Completion 2026-03

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 70 Years
Study Type INTERVENTIONAL
Interventions
ZG005 Powder for InjectionDonafenib Tosilate Tablets

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

Phase 1 is the earliest stage of human testing — safety and dosage are the primary focus. Visits are frequent and medical supervision is intensive. You will be among the first people to receive this treatment.

This trial targets 130 participants in total. It began in 2024-05-10 with a primary completion date of 2026-03.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This is a Multi-center, Open-labe, Phase I/II Study to evaluate the safety and tolerability of ZG005 Combined With Donafenib in Patients With Advanced Solid Tumor.

Eligibility Criteria

Inclusion Criteria: * Fully understand the study and voluntarily sign the informed consent form. * Male or female 18-70 years of age; * Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 or * Life expectancy ≥ 3 months. Exclusion Criteria: * Patients were deemed unsuitable for participating in the study by the investigator for any reasons.

Contact & Investigator

Central Contact

Cheng Wei

✉ weic@zelgen.com

📞 +86-0512-57309965

Principal Investigator

Jason Wu

STUDY CHAIR

Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Frequently Asked Questions

Who can join the NCT06239298 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Solid Tumor. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT06239298 trial and what does that mean for participants?

Phase 1 trials are the first stage of human testing. The primary goal is to assess safety and determine appropriate dosage levels. Participants are closely monitored. These trials typically involve a small number of volunteers.

Is NCT06239298 currently recruiting?

Yes, NCT06239298 is actively recruiting participants. Contact the research team at weic@zelgen.com for enrollment information.

Where is the NCT06239298 trial being conducted?

This trial is being conducted at Chongqing, China.

Who is sponsoring the NCT06239298 clinical trial?

NCT06239298 is sponsored by Suzhou Zelgen Biopharmaceuticals Co.,Ltd. The principal investigator is Jason Wu at Suzhou Zelgen Biopharmaceuticals Co.,Ltd. The trial plans to enroll 130 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology