NCT05886114 A Multi-domain Lifestyle Intervention Among Aged Community-residents in Zhejiang, China
| NCT ID | NCT05886114 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Zhejiang University |
| Condition | Cognitive Impairment |
| Study Type | INTERVENTIONAL |
| Enrollment | 1,200 participants |
| Start Date | 2023-05-28 |
| Primary Completion | 2025-04-28 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 1,200 participants in total. It began in 2023-05-28 with a primary completion date of 2025-04-28.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
A study conducted in Finland discovered that a multidomain intervention, consisting of physical activity, nutritional guidance, cognitive training, social activities, and management of vascular risk factors, effectively decelerated cognitive decline in healthy older adults who were at an increased risk of cognitive decline. The HERITAGE study is a 2-year clustered randomized controlled trial (clustered-RCT) that explores the efficacy of a multidomain intervention among 1200 elderly residents with a higher risk of cognitive decline and dementia in Zhejiang Province, China
Eligibility Criteria
Inclusion Criteria: * At risk of cognitive decline: cognitive performance at the mean level or slightly lower than expected for age with no dementia (AD8\>=3 and/or 5-min MoCA \>, \< 11) * Free of physical disabilities that preclude participation in the study * Willing to complete all study-related activities for 24 months * Willing to be randomized to either lifestyle intervention group Exclusion Criteria: * Diagnosed dementia patients * Diagnosed major depression or other neuropsychological diseases * Malignant diseases * Symptomatic cardiovascular disease * Revascularization within one year * Severe loss of vision, hearing or communicative ability
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05886114 clinical trial?
This trial is open to participants of all sexes, aged 60 Years or older, up to 80 Years, studying Cognitive Impairment. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05886114 currently recruiting?
Yes, NCT05886114 is actively recruiting participants. Contact the research team at xuxinsummer@zju.edu.cn for enrollment information.
Where is the NCT05886114 trial being conducted?
This trial is being conducted at Hangzhou, China.
Who is sponsoring the NCT05886114 clinical trial?
NCT05886114 is sponsored by Zhejiang University. The trial plans to enroll 1,200 participants.