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transformed indolent b cell non hodgkin lymphoma to diffuse large b cell lymphoma
Total Trials
2
Recruiting Now
2
Trial Phases
Phase 2, Phase 1
Lymphoma trials span diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, Hodgkin lymphoma, mantle cell lymphoma, and T-cell lymphomas β€” each with distinct biology and treatment response. CAR-T cell therapy has established a new standard in relapsed/refractory DLBCL, and trials now aim to move this approach earlier in the treatment sequence.
Active trials evaluate bispecific antibodies (mosunetuzumab, epcoritamab, glofitamab), next-generation CAR-T cell products (CD19/CD22 dual targets, BCMA-targeting), BTK inhibitors in B-cell lymphomas, and total metabolic volume on PET as a predictive biomarker for treatment adaptation.
Frequently Asked Questions — transformed indolent b cell non hodgkin lymphoma to diffuse large b cell lymphoma Clinical Trials
How many clinical trials are currently recruiting for transformed indolent b cell non hodgkin lymphoma to diffuse large b cell lymphoma?
ClinicalMetric currently tracks 2 actively recruiting clinical trials for transformed indolent b cell non hodgkin lymphoma to diffuse large b cell lymphoma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 2. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for transformed indolent b cell non hodgkin lymphoma to diffuse large b cell lymphoma?
transformed indolent b cell non hodgkin lymphoma to diffuse large b cell lymphoma research spans Phase 1 (1 trial), Phase 2 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a transformed indolent b cell non hodgkin lymphoma to diffuse large b cell lymphoma clinical trial?
Eligibility criteria for transformed indolent b cell non hodgkin lymphoma to diffuse large b cell lymphoma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1 1
Phase 2 1
Top Sponsors
1 trial
1 trial
Recruiting Clinical Trials
NCT06238648 Phase 2
Recruiting
Enrollment
120 pts
Location
United States
Sponsor
Academic and Community Cancer ...
NCT05755087 Phase 1
Recruiting
Enrollment
18 pts
Location
United States
Sponsor
Lapo Alinari
Related Conditions
diffuse large b cell lymphoma not otherwise specified (1) primary mediastinal large b cell lymphoma (1) recurrent diffuse large b cell lymphoma activated b cell type (1) recurrent diffuse large b cell lymphoma germinal center b cell type (1) recurrent high grade b cell lymphoma with myc and bcl2 or bcl6 rearrangements (1) recurrent high grade b cell lymphoma with myc bcl2 and bcl6 rearrangements (1) refractory diffuse large b cell lymphoma activated b cell type (1) refractory diffuse large b cell lymphoma germinal center b cell type (1) refractory high grade b cell lymphoma with myc and bcl2 or bcl6 rearrangements (1) refractory high grade b cell lymphoma with myc bcl2 and bcl6 rearrangements (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: April 2026 · Data Methodology